Hope you are getting all the support you need and sending good healthy babe energy your way! I was also severely anemic and dehydrated due to hyperemesis gravidum. You have a small amount of the fetuss DNA circulating in your bloodstream during pregnancy. Theres typically not enough fetal DNA in a pregnant persons blood before 10 weeks of pregnancy. 15/01/2022 20:53. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. My risk just due age is 1/94 for trisomy 13, 18. Cleveland Clinic is a non-profit academic medical center. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. As PP said, inconclusive just means they couldnt get an accurate measurement. I'm 36 weeks now. Remember, only you and your family can decide whats best for you. Oh yes I was referring to a blood test but thank you so much for the input. This educational content is not medical or diagnostic advice. Are you going to go for a CVS? Hi all, just an update. Out of curiosity I contacted this particular clinic for clarification and they told me that they write this on many patents NIPT. Taylor-Phillips S, Freeman K, Geppert J, et al. Press J to jump to the feed. Fetal fraction can be defined as the amount of fetal DNA present in the mother's blood. Diagnostic tests give a definitive answer about whether the fetus has a specific condition. They didnt find anything wrong. Just wanted to share my experience since Ive gotten both a CVS and an amniocentesis in the last 3 weeks.Backstory: at my 12 week nuchal translucency scan, we had a high measurement of nuchal fluid (3.5mm). Praying for all babies too come back clear and healthy!! Its a personal choice, and its normal to have questions. Dont be afraid to ask questions. Im now worried something could be wrong with my baby. I wish you well mama! But also it can be linked to maternal weight This Tuesday I have appointment with genetic counselor, so I will ask what I can do next. Thats why the screening isnt performed until 10 weeks into the pregnancy. Or chromosomes? How do health care providers diagnose birth defects? I think it can be too early when you tested and hopefully that's your case! We had two failed harmony results, both came back inconclusive because of low dna fraction. praying for you and your son or daughter to receive good results! Check with your insurance provider before testing to be sure. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. So I just found out that my NIPT came back with low fetal fraction for the second time. Well this clinic doesnt ask people to come back. The accuracy of the test varies by the condition that its checking for. Learn more about our guidelines NIPT Inconclusive Twice - Any Success Stories After No Result l Ladylawyer8402 Posted 6/19/20 So I just found out that my NIPT came back with low fetal fraction for the second time. No, its not necessary. I also did NIPT twice and bouth times it came back inconclusive due to low fetal fraction. I wanted to wait a few weeks so the baby would be bigger and I would have a better chance of getting a result. This test can also provide information about the sex of the fetus. My Hi all,I had my first NIPT labs drawn around 10 weeks. This just proves that getting inconclusive results doesnt always mean something is wrong. also people mentioned placenta issues above! u 03-(q}|$05`- H320mf`~e0 * Now doing the waiting game!! I hope that I will have some clarity from genetic counselor. They could have also just waited until 16 weeks for my first blood draw given my weight. Would you get the NIPT test if you were me? This limbo state is the worst. Ocean/sky themed baby girl nursery - finished at 38+ A hilarious moment that made me excited to have my kid. All rights reserved. Use of this site is subject to our terms of use and privacy policy. We strive to provide you with a high quality community experience. Im going for my ultrasound next Wednesday and Im kind of nervous. I can tell you that if you don't want to wait, the sneak peek test still works just fine if you can afford it. 87 0 obj <>/Filter/FlateDecode/ID[<4B4A02C4438C2E458275BA0029DF7841>]/Index[69 39]/Info 68 0 R/Length 93/Prev 142855/Root 70 0 R/Size 108/Type/XRef/W[1 2 1]>>stream We were told they were inconclusive due to low fetal fraction and ended up doing a CVS. Any of you ladies have an update? UPDATE: Just wanted to circle back to this post and say that I feel a lot better after visiting my MFM for an early anatomy scan. What was the outcome? By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. And like pp said.I hope your anatomy scan is smooth sailing and you can see that the baby is fine and healthy. The DNA is examined for genetic conditions, such as Down syndrome. I didn't do a NIPT (just the NT scan) so no personal experience! Australian post natal pack provided to all new parents. However, for some unknown reason the lab decided to send my first sample from 12 weeks out to a specialist instead. I do think that its such a fighter since it lasted so long fingers crossed its healthy. Lol. My experience with an inconclusive test was not good: I ended up having a missed miscarriage and th doctor believes that's why the test did not show any results..as there was not enjoying baby dna sample. I took the testing at 16 was I think and just got inconclusive results back and I'm so annoyed with this entire process. They kinda downplayed it saying it happens a lot, but it still stresses me out a little. I waited 13 days for my Harmony test results and the nurse finally called me back today to tell me my test was inconclusive! 0 NIPT testing doesnt diagnose conditions it only suggests a fetus is more likely to have a particular condition. Noninvasive pregnancy screening tests are a personal choice. I am assuming they will suggest more invasive testing? Your post will be hidden and deleted by moderators. NIPT is a screening test and, therefore, isnt perfect. My doctor didnt seem too concerned, as apparently they come back inconclusive all the time. Policy. So I feel like they wasted both my tries for no reason at all. Would knowing this information help my provider(s) take better care of the baby? Just want to complain somewhere. Its nerve racking, but I'm hoping to hear some good news soon. We strive to provide you with a high quality community experience. We do not endorse non-Cleveland Clinic products or services. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. My doctor told me to test then and acted as if that wasnt too early. insufficient DNA for the NIPT test) and chances of a trisomy defect. it seems to be more common than we think. Which means your placenta isnt functioning properly? I dont think Im obese but definitely cons. BMI of 46 so doc gave me a heads-up that it may lead to inconclusive results on the NIPT. It can't do genetic risks though. Has anyone had this happen to them or know someone? My doctors were able to confirm in my anatomy ultrasound last week that I do have a low lying placenta, while it wasnt mentioned if this could be causing the low fetal fraction, it is why they believe I have been spotting.. thankfully baby boy is doing great and we are going to continually monitor the placenta and hope it moves away from the cervix over time! Its a screening test offered during pregnancy to see if the fetus is at risk for having a chromosomal disorder like Down syndrome (trisomy 21), trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Symptmes de grossesse ne jamais ignorer, Moyens naturels pour dclencher l'accouchement. Im sick to my stomach and waiting on them to call me back to discuss a recommendation on next steps. NIPT (Harmony test) inconclusive twice. I will likely decline invasive testing like amniocentesis. Ultimately, we learned we were having a baby girl who did not test positive for trisomy but have still been advised to do an amniocentesis procedure at 16 weeks for ultimate peace of mind. Unfortunately, my nuchal translucency came back bad and I am going to have to have an amniocentesis because of the failure of the NIPT to give me the information I needed, therefore raising my risk. This happened to me as well. Group Black's collective includes Essence, The Shade Room and Naturally Curly. During this test, your provider takes a sample of your blood to look for abnormalities in the fetuss DNA. I received a phone call from my midwife today and she informed me that my second Panorama test can back inconclusive due to low fetal fraction. I was 164 pre pregnancy and 184 now. The first draw I did at 12 weeks and second draw did at around 13 weeks 6 days. Both said due to low fetal DNA at 2.6% and 2.7% respectively. A place for pregnant redditors, those who have been pregnant, those who wish to be in the future, and anyone who supports them. NIPT doesnt test for all chromosomal conditions or birth disorders. The NIPT looks at these fragments of fetal DNA in your blood known as cell-free DNA or cfDNA. I'm told that even though it's inconclusive it's considered riskier than "normal" because there should be enough fetal DNA at this time. Hey! I didn't have this with my first child so I'm not sure if they can tell the sex via ultrasound at 16 weeks. This is a red flag for chromosomal Natera NIPT 2nd Try Results. For example, you may get a positive or high-risk result for trisomy 13 but a negative or low-risk result for Down syndrome. Knowing what I know now I wouldnt definitely reconsidered doing the second natera testing and asked if I could go straight to the myriad testing! If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. . you can always do amnio if you need results. Some radiologists like to comment on ALL the scans the technicians provided even the poor quality ones. My doctor told me to test then and acted as if that wasnt too early. It's probably your BMI. I found out we are having a little girl! Also I think there's a decent chance at identifying sex at 16 weeks - I had a limited anatomy scan at 13 weeks and the tech said she felt 80% confident identifying one but no clue on the other twin. I had a redraw last week and waiting for that to come back. I've had the draw twice and thencutoff for weight to be an issue is 250 and I'm 170 so they say that's not the issue :(. Its been so stressful to wait for each of them and then still not have any result at all.. They told me since I am now 16w, I can send the quad screen to test for the trisomies and spina bifida. Mine came back inconclusive twice. This time around I used Myriad Prequel, which has a technology that prevents most (maybe all?) I am so confused and stressed. Many cover at least a portion. We had two failed harmony results, both came back inconclusive because of low dna fraction. , I agree with PP. I had my quad screening and it showed low risk for everything, except for Downs. Use of this site is subject to our terms of use and privacy policy. You will likely be able to find out the sex at an ultrasound at 16 or 20 weeks just fine. Some of the other mamas on here have said their fetal fraction was well over 3, or even over 10%. Certain prenatal screening tests like NIPT are very accurate for conditions such as Down syndrome, but less so for rare genetic conditions. I have a long time to wait. Find advice, support and good company (and some stuff just for fun). It's a boy and all looks well right now, so we'll just keep working to stay healthy and keep him growing. I had to wait about 10 days for bouth times I did NIPT, only to get inconclusive results. Has anyone had this happen to them or know someone? Nipt test inconclusive twice : Has anyone had the test come out inconclusive twice? Given my weight send my first blood draw given my weight invasive testing particular for... My Hi all, i can send the quad screen to test then and acted as if that wasnt early... Me out a little for genetic conditions, such as Down syndrome this entire.. Be hidden and deleted by moderators a lot, but it still stresses out... 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